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Tadagra 20 Tadagra-20 (RSM. Cialis Generic - active ingredient-Tadalafil, 20 mg. Trade name: Tadagra-20. Manufacturer - RSM Enterprises (made in India). 10.2016. Tadagra-20 - the trade name of one of the most effective generics Cialis. Each tablet in its composition contains 20 mg of Tadalafil, which is completely equivalent to the original drug. The effect of the drug completely unfolds in all its glory on the 40-50th minute, and ends in 36 hours. This generic Cialis is made on modern technological equipment, which corresponds to all technological norms and rules. The generic manufacturer is RSM Enterprises (India. Pharmacological action or how Cialis works. Cialis works on the same principle as all PDE-5 inhibitors (Viagra, Levitra, Avanafil ...) with only one small difference in the pharmacokinetics of the drug, which is due to the molecular structure of Tadalafil. Due to this very structure, the tadalafil molecule has a great affinity for type-5 phosphodiesterase (PDE-5), which is why this long-lasting effect of exposure, up to 36 hours, is achieved. Today, the mechanism of erection is represented in this way. In the beginning, as a result of visual or tactile perception, the brain is excited, from which the signal is transmitted to the cells of the penis via the spinal cord, which causes the latter to release nitric oxide (NO). Nitric oxide serves as a signal for the synthesis of cyclic guanosine monophosphate (cGMP), which leads to a decrease in the cells of the penile calcium ions (Ca +), which serves as a factor in relaxing the smooth muscles of the IF and filling it with blood. Involuntarily the question arises: what role does Cialis play in all this? The fact is that the organism of any normally functioning person is in homeostasis, that is, in the constancy of the internal environment. And for any change in the internal environment, compensatory mechanisms are developed. With age, bad habits, a sedentary lifestyle and for a number of other reasons, these mechanisms are violated, and the body becomes unable to balance itself. With regard to erection and sexual function, it is expressed in that the abovementioned negative factors (age, etc.) in the tissues of the penis excessively increases the concentration of a special enzyme PDE-5. It is he that cleaves cGMP, thus preventing the release of ions of calcium, in fact, thanks to which the erection begins. Cialis, only serves as a shield that protects cGMP from destruction by the enzyme PDE-5. Cialis has a very good affinity for the enzyme, which explains the long time exposure of the drug. Thanks to this, the patient can take the pill long before he has the opportunity to do it. Cialis showed high efficiency and the lowest percentage of side effects from all currently available inhibitors of PDE-5 on the market. The use of large amounts of food and moderate doses of alcohol, as shown by clinical trials, practically do not affect the pharmacokinetics of Tadalafil, which makes it an excellent tool for amorous affairs.

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Vikalis VX Vx 20mg is having the drug ingredient called Tadalafil 20mg which is used to treat Erectile Dysfunction in Men. Vikalis VX US is also called the Weekend Pill as Vikalis VX.

Vikalis Vx 10mg is having the drug ingredient called Tadalafil 10mg which is used to treat Erectile Dysfunction in Men.

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Brand(s): Vikalis VX

Sold as: Generic Cialis

Manufacturer: Shree Venkatesh

Strength: 5mg / 10mg / 20mg / 40mg /60mg

Packaging: Blister of 10 Tablets